Natural Herbs for Depression and Anxiety for 2024

According to the Anxiety & Depression Association of America, more than 40 million adults are battling anxiety every year year in the US. Postpartum depression rates can be as high as one in five, and depression amongst teens is just as common.

A combination of therapy and medication is usually the recommended treatment for anxiety and depression. However, natural herbs are also effective for depression, anger, and anxiety. Some of these are also great herbs for postpartum depression.

Best Herbs for Depression and Anxiety

1. Vital Choice MoodCare

Vital Choice MoodCare contains ashwagandha and rhodiola, both natural herbs for treating anxiety and depression.

Ashwagandha, in particular, has been proven as one of the best herbs for depression.

One of the great things about this supplement is that it doesn’t contain any unnecessary ingredients such as artificial colors or preservatives. Vital Choice MoodCare is also suitable for anyone with a dairy or wheat intolerance.

People who use Vital Choice MoodCare have noticed improvements in their mood and levels of anxiety as it helps regulate blood pressure. High blood pressure can make you feel very uncomfortable and anxious, which in turn can make your depression worse. You can expect to see results in just a few days of taking the supplement.

The marine source omega 3 in Vital Choice MoodCare also supports general human cellular health. The fatty acids are extracted from salmon just hours after they are caught to ensure you are getting high-quality nutrients from the fish.


Vital Choice MoodCare can be used to ease the effects of depression and anxiety, but it also has many other health benefits. For people looking for a supplement that is an all-rounder, Vital Choice MoodCare is a great one to consider.

2. Joy-Filled

Joy-Filled supplements are 100% plant-based and contain seven powerful herbs. St. John’s wort, ashwagandha, rhodiola rosea, lemon balm leaf, ginkgo biloba, gotu kola, and eleuthero are the seven potent natural herbs present in Joy-Filled.

The combination of herbs in this supplement are responsible for producing a neurotransmitter called GABA that is responsible for reducing restlessness and calming the mind and body.

First-time users may prefer to take just half a pill at first as it’s very potent. Taking a whole pill daily could make you feel spaced out and disconnected. Slowly but surely, you can work your way up to taking the recommended dosage once your body has gotten used to Joy-Filled.


Joy-Filled is an incredibly potent supplement that contains all of the natural herbs associated with fighting depression and anxiety. It should be taken with care and responsibility, and consulting a doctor may be beneficial for people who have never taken medication or supplements for depression before.

3. Physician’s Choice Ashwa

Physician’s Choice Ashwa is made using 100% USDA-certified organic ashwagandha root powder. The ashwagandha in this supplement doesn’t contain leaves, stems, or fillers, just high-quality pure root powder.

Black pepper is added to Physician’s Choice Ashwa to help it absorb faster into your system. You will see almost instant changes in your mood after taking a capsule.

There are 90 capsules in a packet, and you can take one capsule three times per day, so the pack should last about a month. Physician’s Choice Ashwa is without a doubt one of the best-selling natural supplements on the market.

Many users have reported weight loss as a side effect of taking this supplement. Ashwagandha will naturally reduce cortisol levels in the body, which in turn promotes weight loss.


Not only is Physician’s Choice Ashwa a best seller worldwide, but it also has beneficial weight loss effects for people struggling with stress-related weight gain. If you are underweight, you should consult a doctor before taking this herbal supplement.

4. Natrol 5-HTP Mood and Stress

Natrol 5-HTP Mood and Stress supplement packets contain 60 capsules. The recommended daily dose is just one capsule per day, so one packet should last you two months, which is great value for money.

Natrol 5-HTP Mood and Stress is 100% drug-free and non-habit-forming, which is very appealing to anyone feeling skeptical about taking supplements for depression and anxiety. 5-HTP has been available over-the-counter since 1995 and has been used as a natural way for treating depression ever since.

People suffering from serious negative side effects from prescription medication for anxiety have reported that Natrol 5-HTP Mood and Stress has helped them. This should only be done with the help of a medical professional.


Natrol 5-HTP Mood and Stress supplements are very effective at instantly reducing feelings of stress and anxiety. With that being said, they are not suitable for treating personality disorders such as bipolar.

5. Gaia Herbs St. John’s Wort

Gaia Herbs St. John’s Wort is also an excellent choice among depression and herbal anxiety supplements. The wort is a flowering shrub proven to help ease menopause symptoms, depression, sleep problems, and more. Take a look here if you want to learn about some more of its effects.

Gaia Herbs St. John’s Wort contains 60 pills per packet, which amounts to a 20-day supply. Taking these capsules daily will improve your mood and help you feel overall more positive about life.

Anyone taking prescription drugs should stay away from taking St. John’s Wort as it could interfere with your medication. That is not to say that you can’t take this supplement if you are on medication, but you should hold off until you have spoken to your doctor about it.


Gaia Herbs St. John’s Wort supplement is a high-ticket supplement with great results. If you feel like you fit the criteria for using this supplement, then you are likely to benefit from its anti-depressant qualities.

6. Wholesome Wellness Happy Pills 

Wholesome Wellness Happy Pills are lemon-flavored, which makes taking them much easier for people who struggle to swallow supplements. Herbal pills usually have a strange taste, so these ones are far easier to swallow than most.

Wholesome Wellness Happy Pills contain a combination of herbs in a dosage that is ideal for boosting your mood, which is why they are called Happy Pills. Wholesome Wellness has backed up its product with a 100% satisfaction guarantee. This really boosts your confidence in the product and maybe the nudge you need to give it a try.

Whether you are suffering from menstrual changes such as menopause, age-related mood swings, or trying to overcome trauma, these pills can help you. Wholesome Wellness Happy Pills have a great track record for helping people manage their moods, and they can make you feel better in just a week.


If you don’t see an improvement in your mood or sleep after a couple of weeks of taking Wholesome Wellness Happy Pills, the customer service team will refund your purchase.

7. Enlifta Mood Elevator

Enlifta Mood Elevator supplements have been clinically studied and are blacked by a successful track record. Enlifta offers clients a 100% satisfaction guarantee, which is great considering there are enough tablets in a pack for a month. This gives you four weeks to try Enlifta Mood Elevator and decide whether it works for you without the risk of losing your money.

Furthermore, the supplements are produced in the United States in a GMP facility. This gives you an idea of the high-quality standards expected by the company.

5-Hydroxytryptophan (5-HTP) is the star ingredient in this supplement. Taking this on a daily basis could also improve hot flushes and other menopause side effects.


Enlifta Mood Elevator is a great supplement for targeting mood swings caused by hormonal changes. Users will usually see an improvement in their mood within a week of taking the pills.

8. Trio Nutrition Mood Joy 

Trio Nutrition Mood Joy supplements contain a blend of ashwagandha, St. John’s wort, MCT Oil Powder, 5-HTP, and turmeric. These star ingredients are known to help improve your ability to handle life’s ups and downs.

Trio Nutrition Mood Joy supplements are designed to help you restore the perky mood that has depleted, but you need to be in the right mindset with a will to change for it to work. Your improved mood will help you increase your productivity and promote more restful sleep.

People who have been using this supplement for a long time have reported that they feel a lot more optimistic about life than they did before.


You and the people around you will notice a spring in your step after you take Trio Nutrition Mood Joy for a while. They are great value for money, and you can expect a packet of 60 capsules to last you for 60 days.

9. Garden of Life Dr. Formulated Probiotics Mood+ Acidophilus Probiotic Supplement 

Garden of Life Dr. Formulated Probiotics Mood+ Acidophilus Probiotic Supplement has a vast range of specially formulated supplements to help with various health conditions. This is slightly different from the rest of the supplements on our list as it’s a mood-enhancing probiotic blend of ingredients.

It promotes digestive balance, emotional wellbeing, and relaxation. Garden of Life wants to improve your digestion, mood, and immune system with just one supplement, which makes it an all-rounder.

Garden of Life Dr. Formulated Probiotics Mood+ Acidophilus Probiotic Supplement is a doctor-formulated product, and the ingredients of choice in the supplement that help fight stress and depression are ashwagandha and blueberries. Users shouldn’t take more than two capsules daily.

It’s NON-GMO Project certified and NSF certified gluten-free. These are reliable certifications, so you can trust and consume Garden of Life if you have a gluten intolerance.


If you are looking for a probiotic that has more benefits to your overall well-being than just improved gut health, the Garden of Life is a great option for you. It’s a three-in-one supplement that targets improving your health, immune system, and overall mood. It isn’t as effective as some other more potent supplements on the list, but it’s worth a try if you want a light pick-me-up.

10. Super Calm 

Super Calm liquid drops herbal supplement claims to make you feel relaxed and in control. It contains a blend of 14 herbs that have anti-anxiety effects on your mind and body.

Super Calm can also be used as a vegan sleep aid. Getting a good night’s sleep makes a huge difference to how you feel during the day.

There are plenty of things that interfere with a good night’s sleep. For example, if you live in an area with lots of night traffic, it can interfere with how rested you feel and may even wake you at night. Unfortunately, there isn’t much you can do about that.

Super Calm drops contain adaptogens, kava kava, and passionflower, which help relax muscles and relieve tension from the central nervous system. This supplement also offers added indigestion support for users and is 100% natural and vegan.

Taking liquid supplements is far more convenient than taking tablets, especially for people with digestion problems or low iron. Super Calm drops don’t taste too bad either (compared to other natural supplements), and although you won’t be licking your lips with delight, you won’t need to hold your nose as you take them.

Most people see an improvement in their sleep and anxiety levels within two weeks of taking Super Calm. Sticking to the recommended dosage is extremely important, as taking too much of this supplement may make you feel very unwell.


Super Calm is a great supplement to take if your anxiety is affecting your sleep. This should be taken consistently for a couple of weeks to see if the herb blend is right for you.

Finding Help

Don’t suffer in silence. If you or someone you know is dealing with depression or anxiety, don’t hesitate to ask for help. Life stresses, the international pandemic, and lifestyle changes that we are all going through can be overwhelming, but there is always a helping hand available.

Depression and anxiety have become less of an embarrassing topic for people to talk about, and there is certainly less stigma put on people dealing with these issues. Although society has changed its perspective on the topic, opening up about less than positive feelings is difficult and understandably takes a lot of bravery.

Here are some useful resources with hotline numbers and additional information that can help you overcome any hurdles you are facing:

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